Anti-aging with SignaCell AM
Anti-aging and staying young with Acetyl-L-Carnitine, Alpha Lipoic Acid, and supportive, synergistic amino acids.Each two capsules contain:
SignaCell is the ultimate product for those concerned about Age Related Mitochondrial Decay (AAMD), declining energy production commonly associated with the aging process. The ingredients in SignaCell AM are proven to boost energy metabolism and antioxidant capacity. Our bodies use fatty acids for the production of energy within the mitochondria of every cell. SignaCell provides a patented form of Acetyl-L-Carnitine well known for its role in converting body fat into energy and maintaining the youthful function of cellular metabolism.
This age associated dysfunction (AAMD) appears to be associated with cummulative free radical damage compounded by a lack of important micronutrients in the cell. Acetyl-L-Carnitine and Alpha Lipoic Acid are both endogenous antioxidants that have been shown to help restore natural mitochondrial function and reduce free radical damage. Additionally, Acetyl-L-Carnitine functions to "shuttle" fatty acids across the mitochondrial membrane into the powerhouse of the cell where energy is produced. This proprietary formula also includes supportive and synergistic amino acids L-Arginine, L-Proline, and L-Lysine.Acetyl-L-Carnitine
L-carnitine plays a key role in many bioenergetic processes. Its availability is an important factor controlling not only the utilization of fatty acids and ketone bodies, but also that of glucose and some amino acids. Its primary role is the transport of fatty acids into the mitochondria for the production of energy. L-carnitine is the only carrier used by long chain fatty acids to cross from the cytoplasm through the inner mitochondrial membrane where they undergo B-oxidation and consequent energy production.
Nutritional Uses of L-carnitine
Supplementing the diet with L-carnitine is important for people that want to keep fit and maintain a feeling of general well-being and vitality.
Even marginal deficiencies of essential nutrients like carnitine can reduce endurance, prolong recovery time or make it more difficult to improve performance. The majority of carnitine in the body is found in the skeletal muscles. An increase in metabolism, such as during prolonged exercise, reduces the physiological concentration of free carnitine in the muscle. Supplementing with carnitine can moderately increase this concentration, effecting the regulation of carbohydrate metabolism and preventing the accumulation of lactic acid in the blood and tissues. The result is a faster recovery to the resting value lactate/pyruvate ratio.
Weight management and Energy Enhancement
Without L-carnitine, it would be impossible to burn the amount of fat necessary to produce the energy we need to survive. L-carnitine transports fatty acids into the mitochondria, regulating the amount of fat the body can burn, just like a carburetor regulates the amount of gasoline a car can burn. Because of its role as a regulator in the fat-burning process, it follows that it plays an important role in regulating weight and increasing energy levels.
L-carnitine is a key nutrient for cardiac tissue and has been shown to have clinical benefits. In reduced oxygen conditions, like myocardial ischemia, there is an increase of long chain acyl derivatives. These derivatives damage cell and mitochondrial membranes and inhibit energy production. L-carnitine is the only compound that disperses long-chain acyl derivatives. As such, it improves energy metabolism and maintains cell structure.
As an additional benefit, L-carnitine has been shown to modulate lipid composition by elevating high density lipoproteins (HDL) and reducing serum lipid levels (e.g. lipoprotein). Both are factors which are critical in the prevention of atherosclerosis and heart disease.
Alpha-Lipoic Acid, a lipid and water soluble anti-oxidant, quenches reactive free radicles generated from increased energy production. It may also be instrumental in recycling other antioxidants.
In addition to having antioxidant properties, Alpha Lipoic Acid promotes cellular and muscular energy and functions as a coenzyme in the metabolism of sugars. It is necessary whenever increased energy or strenuous physical activity is required. It also serves as a cofactor for some of the key enzymes (alpha keto acid dehydrogenases) involved in generating energy from food and oxygen in the mitochondria.
Alpha Lipoic Acid helps supply energy to the brain and has been said to boost the effectiveness of the immune system. In Europe, Alpha Lipoic Acid has been promoted for its ability to help maintain and restore liver health.
One of the most beneficial effects of Alpha Lipoic Acid is the ability to regenerate other essential antioxidants such as vitamin C, vitamin E, coenzyme Q10 and glutathione.
Currently, there are both animal and human studies that confirm the use of Alpha Lipoic Acid to prevent and treat diabetes, both Type I and Type II (Adult Onset Diabetes) and their complications. Animal Studies have also shown that Alpha Lipoic Acid can improve glucose utilization in skeletal muscle, the heart muscle and other tissues. One study using Zucker rats as an animal model of obese rats prone to Type II diabetes demonstrated that Alpha Lipoic Acid treatment markedly increased the utilization of glucose in both the absence or presence of insulin. An acute treatment of 100 mg/kg of Alpha Lipoic Acid for one hour or chronic treatment (30 mg/kg for 10 days) produced a 50% improvement in glucose uptake in the skeletal muscles of the experimental animals. (Life Extension, 1996)
For the immune system, it increases the size and activity of the thymus gland which is responsible for manufacturing T-lymphocytes.
In the pancreas, it is used to release insulin.
In the pituitary gland, it is a component of human growth hormone.
In the liver, it assists in neutralizing ammonia.
It is required in muscle metabolism where it helps maintain the nitrogen balance.
In weight control, it facilitates the increase of muscle mass, while reducing body fat.L-Proline & L-Lysine